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Quisinostat
CAS No. 875320-29-9
Quisinostat ( (JNJ-26481585) )
Catalog No. M16360 CAS No. 875320-29-9
Quisinostat (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 70 | In Stock |
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| 5MG | 113 | In Stock |
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| 10MG | 203 | In Stock |
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| 25MG | 314 | In Stock |
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| 50MG | 405 | In Stock |
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| 100MG | 574 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameQuisinostat
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NoteResearch use only, not for human use.
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Brief DescriptionQuisinostat (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11.
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DescriptionQuisinostat (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
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Synonyms(JNJ-26481585)
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC1; HDAC10; HDAC11; HDAC2; HDAC3; HDAC4; HDAC5; HDAC8
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number875320-29-9
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Formula Weight394.48
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Molecular FormulaC21H26N6O2
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Purity>98%(HPLC)
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SolubilityDMSO:79 mg/mL (200.26 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
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SMILESO=C(C1=CN=C(N2CCC(CNCC3=CN(C)C4=C3C=CC=C4)CC2)N=C1)NO
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Chemical NameN-hydroxy-2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Arts J, et al. Clin Cancer Res, 2009, 15(22), 6841-685
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